High-Volume Hemofiltration in Sepsis
نویسندگان
چکیده
منابع مشابه
High-volume hemofiltration in sepsis. Theoretical basis and practical application.
Continuous renal replacement therapy (CRRT) in the ICU is a common treatment in acute renal failure (ARF). CRRT is mainly conceived as merely supportive and as a replacement of the lost kidney function. On the other hand, evidence accumulating over the last years demonstrates that many soluble mediators of the systemic inflammatory (and anti-inflammatory) response syndrome can be removed by CRR...
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In the past decade we have learned a lot about the pathophysiology of septic shock. A lot of experimental research has been performed in vitro and in vivo, showing that hemofiltration can improve hemodynamics and survival. With modern machines, hemofiltration is becoming a sepsis treatment in patients.
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The expression level and prognosis of Toll-like receptor 2 (TLR2) mRNA in peripheral blood mononuclear cells of patients with severe sepsis after applying pulse high-volume hemofiltration (PHVHF) were investigated. Sustained PHVHF treatment was carried out on 40 patients on the basis of conventional treatment for up to 72 h. Acute physiology and chronic health evaluation (APACHE) II scores of p...
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In recent years, a number of techniques have been studied and developed in the field of renal replacement therapy in the septic patient. Manipulation of ultrafiltrate dose, membrane porosity, mode of clearance, and combinations of techniques have yielded promising findings. However, at present, conclusive evidence based on well-designed, randomized controlled trials remains scarce, limiting the...
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Use of high ultrafiltrate flow rates with continuous venovenous hemofiltration (CVVHF) in critically ill patients is an emerging setting, for which there are few data to guide drug dosing. The objectives of this study were, firstly, to investigate the pharmacokinetics of meropenem in critically ill patients with severe sepsis who are receiving high-volume CVVHF with high-volume exchanges (> or ...
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ژورنال
عنوان ژورنال: Nephron
سال: 2002
ISSN: 1660-8151,2235-3186
DOI: 10.1159/000063325